Engineered Cells and Tissues by Locksley McGann

This talk is a little bit about

  • Cellular therapies
  • Tissue transplantation
  • Current and emerging applications
  • Role of analytics in future developments

Cell Therapies and Stem Cells

  • Cell therapies do not necessarily use stem cells
  • Examples:–Blood transfusions–Islets of LangerhansIslets are isolated from the pancreas of a donorand transplanted into a patient to treat diabetes(Edmonton is an international leader in this area)

Adult stem cell examples -3

Umbilical Cord Blood

  • After a baby is born and the umbilical cord is cut, there remains in the cord and the placenta, some of the baby’s blood.
  • This blood, which is normally discarded with the placenta, contains a significant number of hematopoietic stem cells.
  • These hematopoietic stem cells can be cryopreserved for storage, and later used for transplantation.

Looking ahead

  • Therapies utilizing living cells and tissues are increasingly begin used in treating patients
  • Analytics will play an increasingly important role to:–define specific requirements for each patient–design and develop the appropriate biological modalities–monitor the patient to track the performance of the grafted cells/tissues, and to improve procedures
  • These developments require development of partnerships between the disciplines

Learn more from the presentation below: